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#1 2026-06-21 14:21:05

Marlon26L
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Data rejestracji: 2026-06-18
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Has anyone tried combining both NMN and NR for optimal NAD+ elevation?

What's up guys, I've been testing using NMN and NR together for the past couple months and I gotta say the dual action on my energy levels has been quite remarkable - from what I've read, combining nicotinamide mononucleotide and nicotinamide riboside helps since they utilize distinct mechanisms for NAD+ biosynthesis, with NMN likely using the Slc12a8 transporter while NR goes through the NRK1 NRK2 enzymes, so you're essentially targeting NAD+ production from various pathways which appears to boost NAD+ naturally more efficiently than just one alone, and I've experienced better cellular natural energy boosters (https://untenables.com) production plus what feels like more active sirtuin activation for anti-aging effects - I'm currently taking 500mg of NMN in the morning with NR 300mg and including quercetin as a CD38 enzyme inhibitor to reduce NAD+ degradation, though I'm interested if anyone else has tested this combination and what dosages you've

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